Journal: BMC cancer

Article Title: Diagnostic value of circN4BP2L2 in type I and type II epithelial ovarian cancer.

doi: 10.1186/s12885-022-10138-w

Figure Lengend Snippet: Fig. 1 Relative expression level of plasma circN4BP2L2 (a), CA125 (b) and HE4 (c) in type I EOC (n = 70), type II EOC (n = 110), benign ovarian cysts (n = 180) and normal controls (n = 180)

Article Snippet: ELISA analyses were conducted on coded plasma samples to measure the CA125 levels (Quantikine Human CA125 Immunoassay; R&D Systems, Minneapolis, USA) and HE4 concentrations (Quantikine Human HE4 Immunoassay; R&D Systems, Minneapolis, USA) according to the manufacturer’s instructions.

Techniques: Expressing, Clinical Proteomics

Journal: BMC cancer

Article Title: Diagnostic value of circN4BP2L2 in type I and type II epithelial ovarian cancer.

doi: 10.1186/s12885-022-10138-w

Figure Lengend Snippet: Fig. 2 ROC AUC for circN4BP2L2, CA125 and HE4 in type I and type II EOC. It contains ROC AUC for circN4BP2L2 comparing type I EOC with benign (a) and normal (d) cohorts; ROC AUC for CA125 comparing type I EOC with benign (b) and normal (e) cohorts; ROC AUC for HE4 comparing type I EOC with benign (c) and normal (f) cohorts; ROC AUC for circN4BP2L2 comparing type II EOC with benign (h) and normal (k) cohorts; ROC AUC for CA125 compar ing type II EOC with benign (i) and normal (l) cohorts; and ROC AUC for HE4 comparing type II EOC with benign (j) and normal (m) cohorts

Article Snippet: ELISA analyses were conducted on coded plasma samples to measure the CA125 levels (Quantikine Human CA125 Immunoassay; R&D Systems, Minneapolis, USA) and HE4 concentrations (Quantikine Human HE4 Immunoassay; R&D Systems, Minneapolis, USA) according to the manufacturer’s instructions.

Techniques:

Journal: BMC cancer

Article Title: Diagnostic value of circN4BP2L2 in type I and type II epithelial ovarian cancer.

doi: 10.1186/s12885-022-10138-w

Figure Lengend Snippet: Fig. 3 ROC AUC for circN4BP2L2, CA125 and HE4 in type I EOC with regard to tumor stage. It contains ROC AUC for circN4BP2L2 comparing early-stage type I EOC with benign (a) and normal (b) cohorts; ROC AUC for circN4BP2L2 comparing late-stage type I EOC with benign (c) and normal (d) cohorts; ROC AUC for CA125 comparing early-stage type I EOC with benign (e) and normal (f) cohorts; ROC AUC for CA125 comparing late-stage type I EOC with benign (g) and normal (h) cohorts; ROC AUC for HE4 comparing early-stage type I EOC with benign (i) and normal (j) cohorts; and ROC AUC for HE4 comparing late-stage type I EOC with benign (k) and normal (l) cohorts

Article Snippet: ELISA analyses were conducted on coded plasma samples to measure the CA125 levels (Quantikine Human CA125 Immunoassay; R&D Systems, Minneapolis, USA) and HE4 concentrations (Quantikine Human HE4 Immunoassay; R&D Systems, Minneapolis, USA) according to the manufacturer’s instructions.

Techniques:

Journal: BMC cancer

Article Title: Diagnostic value of circN4BP2L2 in type I and type II epithelial ovarian cancer.

doi: 10.1186/s12885-022-10138-w

Figure Lengend Snippet: Fig. 4 ROC AUC for circN4BP2L2, CA125 and HE4 in type II EOC with regard to tumor stage. It contains ROC AUC for circN4BP2L2 comparing early-stage type II EOC with benign (a) and normal (b) cohorts; ROC AUC for circN4BP2L2 comparing late-stage type II EOC with benign (c) and normal (d) cohorts; ROC AUC for CA125 comparing early-stage type II EOC with benign (e) and normal (f) cohorts; ROC AUC for CA125 comparing late-stage type II EOC with benign (g) and normal (h) cohorts; ROC AUC for HE4 comparing early-stage type II EOC with benign (i) and normal (j) cohorts; and ROC AUC for HE4 comparing late-stage type II EOC with benign (k) and normal (l) cohorts

Article Snippet: ELISA analyses were conducted on coded plasma samples to measure the CA125 levels (Quantikine Human CA125 Immunoassay; R&D Systems, Minneapolis, USA) and HE4 concentrations (Quantikine Human HE4 Immunoassay; R&D Systems, Minneapolis, USA) according to the manufacturer’s instructions.

Techniques:

Journal: British Journal of Cancer

Article Title: Improved early detection of ovarian cancer using longitudinal multimarker models

doi: 10.1038/s41416-019-0718-9

Figure Lengend Snippet: a AGR2 serum levels; b LRG1 serum levels; c CHI3L1 serum levels; d FSTL1 serum levels; e SLPI serum levels; f DNAH17 serum levels; g PEBP4 serum levels; h CA125 serum levels; i HE4 serum levels; j glycodelin serum levels. * P < 0.05, ** P < 0.001 from either t test or Mann–Whitney test. Data for borderline cases are omitted. Axis labels: C = controls; I = Type I; II = Type II; L = late; E = early.

Article Snippet: The kits used, catalogue numbers, dilutions, and intra-assay coefficient of variations were: Human AGR2 ELISA Kit (ElabScience; E-EL-H0298; 1:20; 18%), CA125 ECLIA assay (Roche; Elecsys CA 125 II; 1:1; 4%), CHI3L1 Quantikine ELISA Kit (R&D Systems; DC3L10; 1:50; 14%), DNAH17 (human) ELISA Kit (EIAab; E5886h, 1:5; 17%), FSTL1 ELISA Kit (USCN; SEJ085Hu; 1:100; 11%), Glycodelin/PP14 Elisa Kit (Bioserv Diagnostics; BS-30-20; 1:2; 22%), HE4 ECLIA assay (Roche; Elecsys HE 4; 1:1; 8%), LRG1 ELISA Kit (IBL; 27769; 1:2000; 16%), Human PEBP4 ELISA Kit (ElabScience; E-EL-H5440; 1:200; 20%), and SLPI Quantikine ELISA Kit (R&D Systems; DP100, 1:50; 12%).

Techniques: MANN-WHITNEY

Journal: British Journal of Cancer

Article Title: Improved early detection of ovarian cancer using longitudinal multimarker models

doi: 10.1038/s41416-019-0718-9

Figure Lengend Snippet: a AGR2 serum levels; b LRG1 serum levels; c CHI3L1 serum levels; d FSTL1 serum levels; e SLPI serum levels; f DNAH17 serum levels; g PEBP4 serum levels; h CA125 serum levels; i HE4 serum levels; j glycodelin serum levels. * P < 0.05, ** P < 0.001 from either t test or Mann–Whitney test. Data for borderline cases are omitted. Axis labels: C = controls; I = Type I; II = Type II; L = late; E = early.

Article Snippet: The kits used, catalogue numbers, dilutions, and intra-assay coefficient of variations were: Human AGR2 ELISA Kit (ElabScience; E-EL-H0298; 1:20; 18%), CA125 ECLIA assay (Roche; Elecsys CA 125 II; 1:1; 4%), CHI3L1 Quantikine ELISA Kit (R&D Systems; DC3L10; 1:50; 14%), DNAH17 (human) ELISA Kit (EIAab; E5886h, 1:5; 17%), FSTL1 ELISA Kit (USCN; SEJ085Hu; 1:100; 11%), Glycodelin/PP14 Elisa Kit (Bioserv Diagnostics; BS-30-20; 1:2; 22%), HE4 ECLIA assay (Roche; Elecsys HE 4; 1:1; 8%), LRG1 ELISA Kit (IBL; 27769; 1:2000; 16%), Human PEBP4 ELISA Kit (ElabScience; E-EL-H5440; 1:200; 20%), and SLPI Quantikine ELISA Kit (R&D Systems; DP100, 1:50; 12%).

Techniques: MANN-WHITNEY